Coronavirus Disease 2019 (COVID-19) in Italy: Double Reading of Chest CT Examination

To assess the performance of second reading chest compute tomography (CT) examinations by expert radiologists in patients with discordance between reverse transcription real-time fluorescence polymerase chain reaction (RT-PCR) test for COVID-19 viral pneumonia and CT report. Three hundred seventy-eight were included this retrospective study (121 women 257 men; 71 years median age, a range 29–93 years) subjected to RT-PCR tests suspicious infection. All examination order evaluate pulmonary disease involvement COVID-19. images reviewed first two who identified typical patterns then reanalyzed another using structured report diagnosis. Weighted k values used inter-reader agreement. The temporal window RT-PCRs execution scan was zero days (?9, 11) days. positive 328/378 (86.8%). Discordance findings revealed 60 cases. changed diagnosis 16/60 (26.7%) cases contributing an increase concordance RT-PCR. Among these cases, eight false negative RT-PCR, 36 Sensitivity, specificity, predictive value respectively 97.3%, 53.8%, 89.0%, 88.4%. Double scans readers could diagnostic confidence radiological interpretation patients.